Six Antibiotic-Resistant Pathogens Included in This Study:
|Carbapenem-resistant Acinetobacter can survive for a long time on surfaces and frequently contaminates health care facilities. The resulting infections are difficult to treat because they are resistant to most existing antibiotics, and only a few antibiotics in development could potentially be effective against them.
|Carbapenem-resistant Enterobacteriaceae (CRE) is most often a problem in health care settings, primarily with patients who use medical devices such as catheters. CRE infections do not respond to commonly used antibiotics, and some bacteria in this family are resistant to all available antibiotics.
|Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is a family of bacteria (Enterobacteriaceae) that commonly causes infections both inside and outside health care facilities, often in otherwise healthy people. ESBLs are enzymes that break down and destroy commonly used antibiotics, rendering them ineffective.
|Methicillin-resistant Staphylococcus aureus (MRSA) spreads both inside and outside health care facilities and can cause a range of illnesses, including pneumonia and infections of the skin, wounds, and bloodstream. Although treatments for MRSA infections exist, many recommended first-line drugs based on established practice guidelines no longer work.
|Multidrug-resistant Pseudomonas aeruginosa is resistant to many antibiotics, making this bacteria difficult to combat. These infections typically occur in hospitalized patients or people with weakened immune systems.
|Vancomycin-resistant Enterococcus (VRE) is most common in individuals who have spent time in a health care facility such as an intensive care unit or long-term care hospital. This pathogen can cause bloodstream, surgical site, and urinary tract infections.